Studies on the effect of oral and parenteral administration of visammin (khellin) in patients with angina pectoris.

Of 20 carefully studied patients with angina pectoris given oral visammin, 4 had a significant reduction in number of pains. Eleven stated that their pains were less severe and less easily precipitated while taking visammin. There was questionable improvement in the exercise tolerance test in 2 of 9 patients after oral visammin therapy. The daily oral dose ranged from 40 mg. to 240 mg. Undesirable side effects were encountered in 17 of the 20 patients. Parenteral administration of visammin was evaluated by means of the ballistocardiograph, the exercise tolerance test, and by tilting.